Cargando…

Inhibition of lipid metabolism exerts antitumor effects on rhabdomyosarcoma

Rhabdomyosarcoma exhibits tumor‐specific energy metabolic changes that include the Warburg effect. Since targeting cancer metabolism is a promising therapeutic approach, we examined the antitumor effects of suppressing lipid metabolism in rhabdomyosarcoma. We suppressed lipid metabolism in rhabdomyo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miyagaki, Satoshi, Kikuchi, Ken, Mori, Jun, Lopaschuk, Gary D., Iehara, Tomoko, Hosoi, Hajime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446407/ https://www.ncbi.nlm.nih.gov/pubmed/34472721 http://dx.doi.org/10.1002/cam4.4185

Ejemplares similares

Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
por: Ouchi, Kazutaka, et al.
Publicado: (2020)

Reduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma
por: Kanayama, Takuyo, et al.
Publicado: (2021)

In ovo chorioallantoic membrane assay as a xenograft model for pediatric rhabdomyosarcoma
por: Shoji, Chika, et al.
Publicado: (2023)

OBP-801, a novel histone deacetylase inhibitor, induces M-phase arrest and apoptosis in rhabdomyosarcoma cells
por: Tomoyasu, Chihiro, et al.
Publicado: (2019)

Development of non-viral, ligand-dependent, EPHB4-specific chimeric antigen receptor T cells for treatment of rhabdomyosarcoma
por: Kubo, Hiroshi, et al.
Publicado: (2021)

Inhibition of MEK pathway enhances the antitumor efficacy of chimeric antigen receptor T cells against neuroblastoma
por: Tomida, Akimasa, et al.
Publicado: (2021)

Interaction of natural killer cells with neutrophils exerts a significant antitumor immunity in hematopoietic stem cell transplantation recipients
por: Ueda, Ryosuke, et al.
Publicado: (2015)

Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
por: Tenente, Inês M, et al.
Publicado: (2017)

tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
por: Ignatius, Myron S, et al.
Publicado: (2018)

An antitumor peptide RS17‐targeted CD47, design, synthesis, and antitumor activity
por: Wang, Xinmin, et al.
Publicado: (2021)

PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis
por: Kendall, Genevieve C, et al.
Publicado: (2018)

In Vitro and in Vivo antitumor activity and the mechanism of siphonodictyal B in human colon cancer cells
por: Chikamatsu, Sonoko, et al.
Publicado: (2019)

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
por: Marques, Joana G, et al.
Publicado: (2020)

Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
por: Chen, Jiangfei, et al.
Publicado: (2023)

Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway
por: Zhu, Biqiang, et al.
Publicado: (2019)

Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma
por: Nakai, Takaaki, et al.
Publicado: (2017)

Combined ALK and MDM2 inhibition increases antitumor activity and overcomes resistance in human ALK mutant neuroblastoma cell lines and xenograft models
por: Wang, Hui Qin, et al.
Publicado: (2017)

Beta‐blockers exert potent anti‐tumor effects in cutaneous and uveal melanoma
por: Bustamante, Prisca, et al.
Publicado: (2019)

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I
por: Ellinghaus, Peter, et al.
Publicado: (2013)

Construction of a lipid metabolism‐related and immune‐associated prognostic signature for hepatocellular carcinoma
por: Hu, Bo, et al.
Publicado: (2020)

Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma
por: Tran, Gia-Buu, et al.
Publicado: (2023)

Antitumor effects of duvelisib on Epstein–Barr virus‐associated lymphoma cells
por: Kawada, Jun‐ichi, et al.
Publicado: (2018)

The antitumor mechanisms of aerobic exercise: A review of recent preclinical studies
por: Jia, Ningxin, et al.
Publicado: (2021)

Efatutazone and T0901317 exert synergistically therapeutic effects in acquired gefitinib‐resistant lung adenocarcinoma cells
por: Ni, Jie, et al.
Publicado: (2018)

Tanshinone sensitized the antitumor effects of irradiation on laryngeal cancer via JNK pathway
por: Xu, Hui, et al.
Publicado: (2018)

In vitro additive antitumor effects of dimethoxycurcumin and 5‐fluorouracil in colon cancer cells
por: Zhao, Huiying, et al.
Publicado: (2017)

Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway
por: Sun, Ruijie, et al.
Publicado: (2019)

Preimmunization of donor lymphocytes enhances antitumor immunity of autologous hematopoietic stem cell transplantation
por: Suzuki, Koji, et al.
Publicado: (2013)

Endothelial cells express NKG2D ligands and desensitize antitumor NK responses
por: Thompson, Thornton W, et al.
Publicado: (2017)

Strong antitumor efficacy of a pancreatic tumor‐targeting oncolytic adenovirus for neuroendocrine tumors
por: Yamamoto, Yuki, et al.
Publicado: (2017)

Antitumor activity of combined endostatin and thymidine kinase gene therapy in C6 glioma models
por: Chen, Yan, et al.
Publicado: (2016)

Novel anticarcinoembryonic antigen antibody–drug conjugate has antitumor activity in the existence of soluble antigen
por: Shinmi, Daisuke, et al.
Publicado: (2017)

Lethal prognosis of an infant with intraperitoneal large venous malformation
por: Ouchi, Kazutaka, et al.
Publicado: (2021)

Study and analysis of antitumor resistance mechanism of PD1/PD‐L1 immune checkpoint blocker
por: Wang, Zhengyi, et al.
Publicado: (2020)

Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression
por: Huang, Meixian, et al.
Publicado: (2018)

Yarrow supercritical extract exerts antitumoral properties by targeting lipid metabolism in pancreatic cancer
por: Mouhid, Lamia, et al.
Publicado: (2019)

Long non‐coding RNA GAS5 is induced by interferons and plays an antitumor role in esophageal squamous cell carcinoma
por: Huang, Jianbing, et al.
Publicado: (2018)

PGC‐1α inhibits polyamine metabolism in Cyclin E1‐driven ovarian cancer
por: Guo, Ting, et al.
Publicado: (2019)

Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others
por: Kobayashi, Hideaki, et al.
Publicado: (2013)

Energy Metabolism on Mitochondrial Maturation and Its Effects on Cardiomyocyte Cell Fate
por: Persad, Kaya L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e3maku79gi3lv18ik22htm7ucd