Osteogenic Response to Polysaccharide Nanogel Sheets of Human Fibroblasts After Conversion Into Functional Osteoblasts by Direct Phenotypic Cell Reprogramming

Human dermal fibroblasts (HDFs) were converted into osteoblasts using a ALK inhibitor II (inhibitor of transforming growth factor-β signal) on freeze-dried nanogel-cross-linked porous (FD-NanoClip) polysaccharide sheets or fibers. Then, the ability of these directly converted osteoblasts (dOBs) to p...

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Detalles Bibliográficos
Autores principales: Nakai, Kei, Yamamoto, Kenta, Kishida, Tsunao, Kotani, Shin-ichiro, Sato, Yoshiki, Horiguchi, Satoshi, Yamanobe, Hironaka, Adachi, Tetsuya, Boschetto, Francesco, Marin, Elia, Zhu, Wenliang, Akiyoshi, Kazunari, Yamamoto, Toshiro, Kanamura, Narisato, Pezzotti, Giuseppe, Mazda, Osam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446423/
https://www.ncbi.nlm.nih.gov/pubmed/34540813
http://dx.doi.org/10.3389/fbioe.2021.713932

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