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Mechanical Stimulation via Muscle Activity Is Necessary for the Maturation of Tendon Multiscale Mechanics During Embryonic Development

During embryonic development, tendons transform into a hypocellular tissue with robust tensile load-bearing capabilities. Previous work suggests that this mechanical transformation is due to increases in collagen fibril length and is dependent on mechanical stimulation via muscle activity. However,...

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Detalles Bibliográficos
Autores principales: Peterson, Benjamin E., Rolfe, Rebecca A., Kunselman, Allen, Murphy, Paula, Szczesny, Spencer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446456/
https://www.ncbi.nlm.nih.gov/pubmed/34540841
http://dx.doi.org/10.3389/fcell.2021.725563