A rare case of thymoma with CA 19‐9 production

A 72‐year‐old man was diagnosed as having myasthenia gravis (MG). He underwent computed tomography which revealed an anterior mediastinal tumour. Laboratory examination revealed elevated levels (106.3 U/ml) of carbohydrate antigen (CA) 19‐9 in serum. However, no malignant disease was detected on flu...

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Autores principales: Ohashi, Takuya, Kawago, Mitsumasa, Hirai, Yoshimitsu, Kiyoi, Megumi, Miyasaka, Miwako, Yata, Yumi, Kawaji, Mari, Fusamoto, Aya, Iguchi, Hideto, Nakanishi, Hitomi, Nishimura, Yoshiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446695/
https://www.ncbi.nlm.nih.gov/pubmed/34557303
http://dx.doi.org/10.1002/rcr2.844
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author Ohashi, Takuya
Kawago, Mitsumasa
Hirai, Yoshimitsu
Kiyoi, Megumi
Miyasaka, Miwako
Yata, Yumi
Kawaji, Mari
Fusamoto, Aya
Iguchi, Hideto
Nakanishi, Hitomi
Nishimura, Yoshiharu
author_facet Ohashi, Takuya
Kawago, Mitsumasa
Hirai, Yoshimitsu
Kiyoi, Megumi
Miyasaka, Miwako
Yata, Yumi
Kawaji, Mari
Fusamoto, Aya
Iguchi, Hideto
Nakanishi, Hitomi
Nishimura, Yoshiharu
author_sort Ohashi, Takuya
collection PubMed
description A 72‐year‐old man was diagnosed as having myasthenia gravis (MG). He underwent computed tomography which revealed an anterior mediastinal tumour. Laboratory examination revealed elevated levels (106.3 U/ml) of carbohydrate antigen (CA) 19‐9 in serum. However, no malignant disease was detected on fluorodeoxyglucose‐positron emission tomography. A diagnosis of thymoma associated with MG was considered and an extended thymectomy was performed. Histopathologically, thymoma was categorized as stage I based on the Masaoka classification, and as type AB according to the World Health Organization classification. Immunohistochemistry was positive for CA 19‐9. The serum levels returned to the normal range post‐operatively (16.7 U/ml). Herein, we report an extremely rare case of thymoma with raised levels of CA 19‐9.
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spelling pubmed-84466952021-09-22 A rare case of thymoma with CA 19‐9 production Ohashi, Takuya Kawago, Mitsumasa Hirai, Yoshimitsu Kiyoi, Megumi Miyasaka, Miwako Yata, Yumi Kawaji, Mari Fusamoto, Aya Iguchi, Hideto Nakanishi, Hitomi Nishimura, Yoshiharu Respirol Case Rep Case Reports A 72‐year‐old man was diagnosed as having myasthenia gravis (MG). He underwent computed tomography which revealed an anterior mediastinal tumour. Laboratory examination revealed elevated levels (106.3 U/ml) of carbohydrate antigen (CA) 19‐9 in serum. However, no malignant disease was detected on fluorodeoxyglucose‐positron emission tomography. A diagnosis of thymoma associated with MG was considered and an extended thymectomy was performed. Histopathologically, thymoma was categorized as stage I based on the Masaoka classification, and as type AB according to the World Health Organization classification. Immunohistochemistry was positive for CA 19‐9. The serum levels returned to the normal range post‐operatively (16.7 U/ml). Herein, we report an extremely rare case of thymoma with raised levels of CA 19‐9. John Wiley & Sons, Ltd 2021-09-17 /pmc/articles/PMC8446695/ /pubmed/34557303 http://dx.doi.org/10.1002/rcr2.844 Text en © 2021 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Ohashi, Takuya
Kawago, Mitsumasa
Hirai, Yoshimitsu
Kiyoi, Megumi
Miyasaka, Miwako
Yata, Yumi
Kawaji, Mari
Fusamoto, Aya
Iguchi, Hideto
Nakanishi, Hitomi
Nishimura, Yoshiharu
A rare case of thymoma with CA 19‐9 production
title A rare case of thymoma with CA 19‐9 production
title_full A rare case of thymoma with CA 19‐9 production
title_fullStr A rare case of thymoma with CA 19‐9 production
title_full_unstemmed A rare case of thymoma with CA 19‐9 production
title_short A rare case of thymoma with CA 19‐9 production
title_sort rare case of thymoma with ca 19‐9 production
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446695/
https://www.ncbi.nlm.nih.gov/pubmed/34557303
http://dx.doi.org/10.1002/rcr2.844
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