Novel theranostic agent for PET imaging and targeted radiopharmaceutical therapy of tumour-infiltrating immune cells in glioma

BACKGROUND: Malignant gliomas are deadly tumours with few therapeutic options. Although immunotherapy may be a promising therapeutic strategy for treating gliomas, a significant barrier is the CD11b(+) tumour-associated myeloid cells (TAMCs), a heterogeneous glioma infiltrate comprising up to 40% of...

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Detalles Bibliográficos
Autores principales: Foster, Alexandra, Nigam, Shubhanchi, Tatum, David S, Raphael, Itay, Xu, Jide, Kumar, Rajeev, Plakseychuk, Elizabeth, Latoche, Joseph D, Vincze, Sarah, Li, Bo, Giri, Rajan, McCarl, Lauren H, Edinger, Robert, Ak, Murat, Peddagangireddy, Vishal, Foley, Lesley M, Hitchens, T Kevin, Colen, Rivka R, Pollack, Ian F, Panigrahy, Ashok, Magda, Darren, Anderson, Carolyn J, Edwards, W Barry, Kohanbash, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446777/
https://www.ncbi.nlm.nih.gov/pubmed/34530385
http://dx.doi.org/10.1016/j.ebiom.2021.103571

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