Cannabinoid receptor interacting protein 1a interacts with myristoylated Gα(i) N terminus via a unique gapped β-barrel structure

Cannabinoid receptor interacting protein 1a (CRIP1a) modulates CB(1) cannabinoid receptor G-protein coupling in part by altering the selectivity for Gα(i) subtype activation, but the molecular basis for this function of CRIP1a is not known. We report herein the first structure of CRIP1a at a resolut...

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Detalles Bibliográficos
Autores principales: Booth, William T., Clodfelter, Jill E., Leone-Kabler, Sandra, Hughes, Erin K., Eldeeb, Khalil, Howlett, Allyn C., Lowther, W. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Accelerated Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446797/
https://www.ncbi.nlm.nih.gov/pubmed/34418434
http://dx.doi.org/10.1016/j.jbc.2021.101099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446797/
https://www.ncbi.nlm.nih.gov/pubmed/34418434
http://dx.doi.org/10.1016/j.jbc.2021.101099

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