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Combination treatment of liposomal amphotericin B and isavuconazole is synergistic in treating experimental mucormycosis

OBJECTIVES: Liposomal amphotericin B (L-AMB) and isavuconazonium sulphate are commonly used antifungal drugs to treat mucormycosis. However, the efficacy of combination therapy of L-AMB/isavuconazonium sulphate versus monotherapy is unknown. We used an immunosuppressed mouse model of pulmonary mucor...

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Detalles Bibliográficos
Autores principales:	Gebremariam, Teclegiorgis, Gu, Yiyou, Singh, Shakti, Kitt, Therese M, Ibrahim, Ashraf S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446914/ https://www.ncbi.nlm.nih.gov/pubmed/34263306 http://dx.doi.org/10.1093/jac/dkab233

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