Cargando…

Exploiting Electrostatic Interaction for Highly Sensitive Detection of Tumor-Derived Extracellular Vesicles by an Electrokinetic Sensor

[Image: see text] We present an approach to improve the detection sensitivity of a streaming current-based biosensor for membrane protein profiling of small extracellular vesicles (sEVs). The experimental approach, supported by theoretical investigation, exploits electrostatic charge contrast betwee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sahu, Siddharth Sourabh, Cavallaro, Sara, Hååg, Petra, Nagy, Ábel, Karlström, Amelie Eriksson, Lewensohn, Rolf, Viktorsson, Kristina, Linnros, Jan, Dev, Apurba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447189/ https://www.ncbi.nlm.nih.gov/pubmed/34473477 http://dx.doi.org/10.1021/acsami.1c13192

Ejemplares similares

Comparison and optimization of nanoscale extracellular vesicle imaging by scanning electron microscopy for accurate size-based profiling and morphological analysis
por: Cavallaro, Sara, et al.
Publicado: (2021)

Characterizing single extracellular vesicles by droplet barcode sequencing for protein analysis
por: Banijamali, Mahsan, et al.
Publicado: (2022)

Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCR
por: Stiller, Christiane, et al.
Publicado: (2021)

Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome
por: Viktorsson, Kristina, et al.
Publicado: (2022)

EPHA2 Interacts with DNA-PK(cs) in Cell Nucleus and Controls Ionizing Radiation Responses in Non-Small Cell Lung Cancer Cells
por: Kaminskyy, Vitaliy O., et al.
Publicado: (2021)

DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines
por: Salim, Hogir, et al.
Publicado: (2015)

Cytotoxic Alkylynols of the Sponge Cribrochalina vasculum: Structure, Synthetic Analogs and SAR Studies
por: Kovalerchik, Dimitry, et al.
Publicado: (2022)

Chemosensitization by phenothiazines in human lung cancer cells: impaired resolution of γH2AX and increased oxidative stress elicit apoptosis associated with lysosomal expansion and intense vacuolation
por: Zong, D, et al.
Publicado: (2011)

Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells
por: Zovko, Ana, et al.
Publicado: (2016)

Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest
por: Lundholm, L, et al.
Publicado: (2013)

The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy
por: Tendler, Salomon, et al.
Publicado: (2020)

Caspase-2 is a mediator of apoptotic signaling in response to gemtuzumab ozogamicin in acute myeloid leukemia
por: Hååg, Petra, et al.
Publicado: (2022)

Harnessing the lysosome-dependent antitumor activity of phenothiazines in human small cell lung cancer
por: Zong, D, et al.
Publicado: (2014)

Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer
por: Efazat, Ghazal, et al.
Publicado: (2016)

Systems biology approaches to develop innovative strategies for lung cancer therapy
por: Viktorsson, K, et al.
Publicado: (2014)

Rapid Detection and Trapping of Extracellular Vesicles by Electrokinetic Concentration for Liquid Biopsy on Chip
por: Cheung, Lucia S., et al.
Publicado: (2018)

Ultrasensitive photodetectors exploiting electrostatic trapping and percolation transport
por: Zhang, Yingjie, et al.
Publicado: (2016)

Electrokinetics and electrohydrodynamics in microsystems
por: Ramos, Antonio, et al.
Publicado: (2011)

Preclinical Evaluation of the GRPR-Targeting Antagonist RM26 Conjugated to the Albumin-Binding Domain for GRPR-Targeting Therapy of Cancer
por: Abouzayed, Ayman, et al.
Publicado: (2020)

Fine-Tuning Electrokinetic Injections Considering Nonlinear Electrokinetic Effects in Insulator-Based Devices
por: Miller, Abbi, et al.
Publicado: (2021)

APS8, a Polymeric Alkylpyridinium Salt Blocks α7 nAChR and Induces Apoptosis in Non-Small Cell Lung Carcinoma
por: Zovko, Ana, et al.
Publicado: (2013)

Tumor treating fields (TTFields) delay DNA damage repair following radiation treatment of glioma cells
por: Giladi, Moshe, et al.
Publicado: (2017)

Multiplex immune protein profiling of fine‐needle aspirates from patients with non‐small‐cell lung cancer reveals signatures associated with PD‐L1 expression and tumor stage
por: Franzén, Bo, et al.
Publicado: (2021)

Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells
por: Alkasalias, Twana, et al.
Publicado: (2022)

Correction: Proof-of-principle studies on a strategy to enhance nucleotide imbalance specifically in cancer cells
por: Alkasalias, Twana, et al.
Publicado: (2022)

Stability Enhancement of a Dimeric HER2-Specific Affibody Molecule through Sortase A-Catalyzed Head-to-Tail Cyclization
por: Westerlund, Kristina, et al.
Publicado: (2021)

ELECTROKINETIC PHENOMENA : IX. ELECTROPHORESIS AND ELECTROOSMOSIS
por: Abramson, Harold A.
Publicado: (1932)

CISM lecture on electrokinetics and electrohydrodynamics in microsystems
por: Ramos, Antonio
Publicado: (2011)

Liquid Crystals-Enabled AC Electrokinetics
por: Peng, Chenhui, et al.
Publicado: (2019)

Deformability-Based Electrokinetic Particle Separation
por: Zhou, Teng, et al.
Publicado: (2016)

Axial electrokinetic trapping of anisotropic particles
por: Strubbe, Filip, et al.
Publicado: (2019)

Electrokinetic characterization of synthetic protein nanoparticles
por: Quevedo, Daniel F, et al.
Publicado: (2020)

A Focus on Two Electrokinetics Issues
por: Dai, Cheng, et al.
Publicado: (2020)

ELECTROKINETICS : XVII. SURFACE CHARGE AND ION ANTAGONISM
por: Moyer, Laurence S., et al.
Publicado: (1935)

Water Flux and Electrokinetic Phenomena in the Squid Axon
por: Vargas, Fernando F.
Publicado: (1968)

Modeling the AC Electrokinetic Behavior of Semiconducting Spheres
por: García-Sánchez, Pablo, et al.
Publicado: (2019)

Thermometry of photosensitive and optically induced electrokinetics chips
por: Wang, Feifei, et al.
Publicado: (2018)

Electrokinetic Phenomena in Pencil Lead-Based Microfluidics
por: Bashirzadeh, Yashar, et al.
Publicado: (2016)

Electrokinetic droplet transport from electroosmosis to electrophoresis
por: Bazarenko, Andrei, et al.
Publicado: (2018)

AC electrokinetic immobilization of organic dye molecules
por: Laux, Eva-Maria, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o0kudn6eot3bff4l21ctng2mho