Folate hydrolase‐1 (FOLH1) is a novel target for antibody‐based brachytherapy in Merkel cell carcinoma

BACKGROUNDS: Folate Hydrolase‐1 (FOLH1; PSMA) is a type II transmembrane protein, luminally expressed by solid tumour neo‐vasculature. Monoclonal antibody (mAb), J591, is a vehicle for mAb‐based brachytherapy in FOLH1+ cancers. Brachytherapy is a form of radiotherapy that involves placing a radioact...

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Detalles Bibliográficos
Autores principales: Ramirez‐Fort, M. K., Meier‐Schiesser, B., Lachance, K., Mahase, S. S., Church, C. D., Niaz, M. J., Liu, H., Navarro, V., Nikolopoulou, A., Kazakov, D. V., Contassot, E., Nguyen, D. P., Sach, J., Hadravsky, L., Sheng, Y., Tagawa, S. T., Wu, X., Lange, C. S., French, L. E., Nghiem, P. T., Bander, N. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447486/
https://www.ncbi.nlm.nih.gov/pubmed/34541577
http://dx.doi.org/10.1002/ski2.9

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