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A deletion in the N gene may cause diagnostic escape in SARS-CoV-2 samples
Five SARS-CoV-2-positive samples showed N-gene drop-out with a RT-PCR multiplex test. WGS found all samples to harbor a deletion in the same region of the N gene, which is likely to impair the efficiency of amplification. This highlights the need for a continued surveillance of viral evolution and d...
Autores principales: | Zannoli, Silvia, Dirani, Giorgio, Taddei, Francesca, Gatti, Giulia, Poggianti, Ilaria, Denicolò, Agnese, Arfilli, Valentina, Manera, Martina, Mancini, Andrea, Battisti, Arianna, Sambri, Vittorio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447549/ https://www.ncbi.nlm.nih.gov/pubmed/34649189 http://dx.doi.org/10.1016/j.diagmicrobio.2021.115540 |
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