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A TP53 mutation model for the prediction of prognosis and therapeutic responses in head and neck squamous cell carcinoma

BACKGROUND: Tumor protein p53 (TP53) is the most frequently mutated gene in head and neck squamous cell carcinoma (HNSC), and TP53 mutations are associated with inhibited immune signatures and poor prognosis. We established a TP53 mutation associated risk score model to evaluate the prognosis and th...

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Detalles Bibliográficos
Autores principales: Shi, Congyu, Liu, Shan, Tian, Xudong, Wang, Xiaoyi, Gao, Pan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447564/
https://www.ncbi.nlm.nih.gov/pubmed/34530752
http://dx.doi.org/10.1186/s12885-021-08765-w