Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER‐phagy, and Collagen quality control

Degradation of the endoplasmic reticulum (ER) via selective autophagy (ER‐phagy) is vital for cellular homeostasis. We identify FAM134A/RETREG2 and FAM134C/RETREG3 as ER‐phagy receptors, which predominantly exist in an inactive state under basal conditions. Upon autophagy induction and ER stress sig...

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Detalles Bibliográficos
Autores principales: Reggio, Alessio, Buonomo, Viviana, Berkane, Rayene, Bhaskara, Ramachandra M, Tellechea, Mariana, Peluso, Ivana, Polishchuk, Elena, Di Lorenzo, Giorgia, Cirillo, Carmine, Esposito, Marianna, Hussain, Adeela, Huebner, Antje K, Hübner, Christian A, Settembre, Carmine, Hummer, Gerhard, Grumati, Paolo, Stolz, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447607/
https://www.ncbi.nlm.nih.gov/pubmed/34338405
http://dx.doi.org/10.15252/embr.202052289

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