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TLR7 is expressed by support cells, but not sensory neurons, in ganglia

BACKGROUND: Toll-like receptor 7 (TLR7) is an innate immune receptor that detects viral single-stranded RNA and triggers the production of proinflammatory cytokines and type 1 interferons in immune cells. TLR7 agonists also modulate sensory nerve function by increasing neuronal excitability, althoug...

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Detalles Bibliográficos
Autores principales: Proskocil, Becky J., Wai, Karol, Lebold, Katherine M., Norgard, Mason A., Michaelis, Katherine A., De La Torre, Ubaldo, Cook, Madeline, Marks, Daniel L., Fryer, Allison D., Jacoby, David B., Drake, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447680/
https://www.ncbi.nlm.nih.gov/pubmed/34530852
http://dx.doi.org/10.1186/s12974-021-02269-x