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Hi-C profiling of cancer spheroids identifies 3D-growth-specific chromatin interactions in breast cancer endocrine resistance

BACKGROUND: Organoids or spheroids have emerged as a physiologically relevant in vitro preclinical model to study patient-specific diseases. A recent study used spheroids of MCF10 cells to model breast cancer progression and identified targetable alterations more similar to those in vivo. Thus, it i...

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Detalles Bibliográficos
Autores principales:	Li, Jingwei, Fang, Kun, Choppavarapu, Lavanya, Yang, Ke, Yang, Yini, Wang, Junbai, Cao, Ruifeng, Jatoi, Ismail, Jin, Victor X.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447690/ https://www.ncbi.nlm.nih.gov/pubmed/34535185 http://dx.doi.org/10.1186/s13148-021-01167-6

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