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Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes

BACKGROUND: Sphingosine Kinase (SphK) that catalyzes sphingosine (Sph) to sphingosine 1-phosphate (S1P), plays a key role in both sphingolipid metabolism and cellular signaling. While SphK has been implicated in type 2 diabetes mellitus (T2DM), it is unexplored in humans. Herein, we investigated whe...

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Detalles Bibliográficos
Autores principales:	Chen, Qi, Wang, Wei, Xia, Ming-Feng, Lu, You-li, Bian, Hua, Yu, Chen, Li, Xiao-Ying, Vadas, Mathew A., Gao, Xin, Lin, Huan-Dong, Xia, Pu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447705/ https://www.ncbi.nlm.nih.gov/pubmed/34530846 http://dx.doi.org/10.1186/s12967-021-03066-z

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