Malignant hyperthermia in severe COVID-19: 2 case reports

Malignant hyperthermia is a rare but potentially fatal condition. We present 2 cases of young patients with coronavirus disease 2019 (COVID-19) requiring intubation for hypoxic respiratory failure who both developed significant hyperthermia post intubation and were suspected to have malignant hypert...

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Autores principales: Ehteshami-Afshar, Solmaz, Nikooie, Roozbeh, Reddy, Pranav, Chichra, Astha, Siegel, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447731/
http://dx.doi.org/10.1097/EC9.0000000000000013
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author Ehteshami-Afshar, Solmaz
Nikooie, Roozbeh
Reddy, Pranav
Chichra, Astha
Siegel, Mark D.
author_facet Ehteshami-Afshar, Solmaz
Nikooie, Roozbeh
Reddy, Pranav
Chichra, Astha
Siegel, Mark D.
author_sort Ehteshami-Afshar, Solmaz
collection PubMed
description Malignant hyperthermia is a rare but potentially fatal condition. We present 2 cases of young patients with coronavirus disease 2019 (COVID-19) requiring intubation for hypoxic respiratory failure who both developed significant hyperthermia post intubation and were suspected to have malignant hyperthermia. However, the 2 patients had different responses to conservative management and dantrolene. These cases highlight the increased challenge imposed by intubation complications when managing patients with COVID-19.
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spelling pubmed-84477312021-09-20 Malignant hyperthermia in severe COVID-19: 2 case reports Ehteshami-Afshar, Solmaz Nikooie, Roozbeh Reddy, Pranav Chichra, Astha Siegel, Mark D. Emergency and Critical Care Medicine Case Report Malignant hyperthermia is a rare but potentially fatal condition. We present 2 cases of young patients with coronavirus disease 2019 (COVID-19) requiring intubation for hypoxic respiratory failure who both developed significant hyperthermia post intubation and were suspected to have malignant hyperthermia. However, the 2 patients had different responses to conservative management and dantrolene. These cases highlight the increased challenge imposed by intubation complications when managing patients with COVID-19. 2021-09-15 /pmc/articles/PMC8447731/ http://dx.doi.org/10.1097/EC9.0000000000000013 Text en Copyright © 2021 Shandong University, published by Wolters Kluwer, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Case Report
Ehteshami-Afshar, Solmaz
Nikooie, Roozbeh
Reddy, Pranav
Chichra, Astha
Siegel, Mark D.
Malignant hyperthermia in severe COVID-19: 2 case reports
title Malignant hyperthermia in severe COVID-19: 2 case reports
title_full Malignant hyperthermia in severe COVID-19: 2 case reports
title_fullStr Malignant hyperthermia in severe COVID-19: 2 case reports
title_full_unstemmed Malignant hyperthermia in severe COVID-19: 2 case reports
title_short Malignant hyperthermia in severe COVID-19: 2 case reports
title_sort malignant hyperthermia in severe covid-19: 2 case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447731/
http://dx.doi.org/10.1097/EC9.0000000000000013
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AT chichraastha malignanthyperthermiainseverecovid192casereports
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