Study TPX-100-5: intra-articular TPX-100 significantly delays pathological bone shape change and stabilizes cartilage in moderate to severe bilateral knee OA

BACKGROUND: TPX-100, a promotor of osteoblast and chondroblast differentiation, is a potential osteoarthritis (OA) therapy. This retrospective study compared MRI 3D femoral bone shape changes (B-scores) after intra-articular TPX-100 or placebo and analyzed the relationship between cartilage thicknes...

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Detalles Bibliográficos
Autores principales: McGuire, Dawn, Bowes, Michael, Brett, Alan, Segal, Neil A., Miller, Meghan, Rosen, David, Kumagai, Yoshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447757/
https://www.ncbi.nlm.nih.gov/pubmed/34535197
http://dx.doi.org/10.1186/s13075-021-02622-8

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