Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021

We describe two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in th...

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Autores principales: Sabat, Artur J, Bathoorn, Erik, Chlebowicz-Fliss, Monika A, Akkerboom, Viktoria, Kamphuis, Inge, dos Santos, Claudy Oliveira, Friedrich, Alexander W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447827/
https://www.ncbi.nlm.nih.gov/pubmed/34533121
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.37.2100800
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author Sabat, Artur J
Bathoorn, Erik
Chlebowicz-Fliss, Monika A
Akkerboom, Viktoria
Kamphuis, Inge
dos Santos, Claudy Oliveira
Friedrich, Alexander W
author_facet Sabat, Artur J
Bathoorn, Erik
Chlebowicz-Fliss, Monika A
Akkerboom, Viktoria
Kamphuis, Inge
dos Santos, Claudy Oliveira
Friedrich, Alexander W
author_sort Sabat, Artur J
collection PubMed
description We describe two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in the northern Netherlands. Variations between the two isolate genomes indicate that this MRSA strain might have been spreading for some time and could have disseminated to other regions of the Netherlands and other European countries.
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spelling pubmed-84478272021-10-13 Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021 Sabat, Artur J Bathoorn, Erik Chlebowicz-Fliss, Monika A Akkerboom, Viktoria Kamphuis, Inge dos Santos, Claudy Oliveira Friedrich, Alexander W Euro Surveill Rapid Communication We describe two false-negative results in the detection of meticillin-resistant Staphylococcus aureus (MRSA) of sequence type 398 and spa type t011 using the Cepheid Xpert MRSA NxG assay. The isolates were recovered in late February and early March 2021 from two patients in different hospitals in the northern Netherlands. Variations between the two isolate genomes indicate that this MRSA strain might have been spreading for some time and could have disseminated to other regions of the Netherlands and other European countries. European Centre for Disease Prevention and Control (ECDC) 2021-09-16 /pmc/articles/PMC8447827/ /pubmed/34533121 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.37.2100800 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Sabat, Artur J
Bathoorn, Erik
Chlebowicz-Fliss, Monika A
Akkerboom, Viktoria
Kamphuis, Inge
dos Santos, Claudy Oliveira
Friedrich, Alexander W
Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title_full Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title_fullStr Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title_full_unstemmed Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title_short Misidentification of meticillin-resistant Staphylococcus aureus by the Cepheid Xpert MRSA NxG assay, the Netherlands, February to March 2021
title_sort misidentification of meticillin-resistant staphylococcus aureus by the cepheid xpert mrsa nxg assay, the netherlands, february to march 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447827/
https://www.ncbi.nlm.nih.gov/pubmed/34533121
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.37.2100800
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