Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases

Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion‐positive lung cancer, selecting sequential ALK‐tyrosine kinase inhibitors, confirming...

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Autores principales: Mitsumura, Takahiro, Kumaki, Yuichi, Takahashi, Kenta, Matsudera, Shotaro, Sakakibara, Rie, Honda, Takayuki, Ishizuka, Masahiro, Iijima, Yuki, Shirai, Tsuyoshi, Okamoto, Tsukasa, Tateishi, Tomoya, Sakashita, Hiroyuki, Miyake, Satoshi, Ikeda, Sadakatsu, Miyazaki, Yasunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447906/
https://www.ncbi.nlm.nih.gov/pubmed/34378333
http://dx.doi.org/10.1111/1759-7714.14098
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author Mitsumura, Takahiro
Kumaki, Yuichi
Takahashi, Kenta
Matsudera, Shotaro
Sakakibara, Rie
Honda, Takayuki
Ishizuka, Masahiro
Iijima, Yuki
Shirai, Tsuyoshi
Okamoto, Tsukasa
Tateishi, Tomoya
Sakashita, Hiroyuki
Miyake, Satoshi
Ikeda, Sadakatsu
Miyazaki, Yasunari
author_facet Mitsumura, Takahiro
Kumaki, Yuichi
Takahashi, Kenta
Matsudera, Shotaro
Sakakibara, Rie
Honda, Takayuki
Ishizuka, Masahiro
Iijima, Yuki
Shirai, Tsuyoshi
Okamoto, Tsukasa
Tateishi, Tomoya
Sakashita, Hiroyuki
Miyake, Satoshi
Ikeda, Sadakatsu
Miyazaki, Yasunari
author_sort Mitsumura, Takahiro
collection PubMed
description Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion‐positive lung cancer, selecting sequential ALK‐tyrosine kinase inhibitors, confirming uncommon EGFR mutations, and receiving biomarker‐compatible therapy.
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spelling pubmed-84479062021-09-22 Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases Mitsumura, Takahiro Kumaki, Yuichi Takahashi, Kenta Matsudera, Shotaro Sakakibara, Rie Honda, Takayuki Ishizuka, Masahiro Iijima, Yuki Shirai, Tsuyoshi Okamoto, Tsukasa Tateishi, Tomoya Sakashita, Hiroyuki Miyake, Satoshi Ikeda, Sadakatsu Miyazaki, Yasunari Thorac Cancer Case Reports Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion‐positive lung cancer, selecting sequential ALK‐tyrosine kinase inhibitors, confirming uncommon EGFR mutations, and receiving biomarker‐compatible therapy. John Wiley & Sons Australia, Ltd 2021-08-10 2021-09 /pmc/articles/PMC8447906/ /pubmed/34378333 http://dx.doi.org/10.1111/1759-7714.14098 Text en © 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Mitsumura, Takahiro
Kumaki, Yuichi
Takahashi, Kenta
Matsudera, Shotaro
Sakakibara, Rie
Honda, Takayuki
Ishizuka, Masahiro
Iijima, Yuki
Shirai, Tsuyoshi
Okamoto, Tsukasa
Tateishi, Tomoya
Sakashita, Hiroyuki
Miyake, Satoshi
Ikeda, Sadakatsu
Miyazaki, Yasunari
Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title_full Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title_fullStr Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title_full_unstemmed Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title_short Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases
title_sort treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): a review of three cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447906/
https://www.ncbi.nlm.nih.gov/pubmed/34378333
http://dx.doi.org/10.1111/1759-7714.14098
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