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Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury

BACKGROUND: Sphingolipids produce pleiotropic signaling pathways, and participate in the pathological mechanism of hepatocyte apoptosis and necrosis during liver injury. However, the role of glucosylceramide synthase (GCS)–key enzyme that catalyzes the first glycosylation step, in liver injury is st...

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Detalles Bibliográficos
Autores principales:	Gan, Jian, Gao, Qin, Wang, Li Li, Tian, Ai Ping, Zhu, Long Dong, Zhang, Li Ting, Zhou, Wei, Mao, Xiao Rong, Li, Jun Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447939/ https://www.ncbi.nlm.nih.gov/pubmed/34611503 http://dx.doi.org/10.7717/peerj.12138

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