Cargando…
Continuous flow asymmetric synthesis of chiral active pharmaceutical ingredients and their advanced intermediates
Catalytic enantioselective transformations provide well-established and direct access to stereogenic synthons that are broadly distributed among active pharmaceutical ingredients (APIs). These reactions have been demonstrated to benefit considerably from the merits of continuous processing and micro...
Autores principales: | Ötvös, Sándor B., Kappe, C. Oliver |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447942/ https://www.ncbi.nlm.nih.gov/pubmed/34671222 http://dx.doi.org/10.1039/d1gc01615f |
Ejemplares similares
-
Multigram-scale flow synthesis of the chiral key intermediate of (–)-paroxetine enabled by solvent-free heterogeneous organocatalysis
por: Ötvös, Sándor B., et al.
Publicado: (2019) -
A Telescoped Continuous
Flow Enantioselective Process
for Accessing Intermediates of 1-Aryl-1,3-diols as Chiral Building
Blocks
por: Maestro, Aitor, et al.
Publicado: (2023) -
Telescoped Continuous Flow Synthesis of Optically
Active γ-Nitrobutyric Acids as Key Intermediates of Baclofen,
Phenibut, and Fluorophenibut
por: Ötvös, Sándor B., et al.
Publicado: (2020) -
Continuous‐Flow Amide and Ester Reductions Using Neat Borane Dimethylsulfide Complex
por: Ötvös, Sándor B., et al.
Publicado: (2020) -
The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry
por: Baumann, Marcus, et al.
Publicado: (2015)