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Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report
RATIONALE: Solitary bone plasmacytoma (SBP) is a rare manifestation of plasma cell tumor. Although axial skeleton is the most frequently affected site of SBP, adjacent disc space involvement is rare. Herein we report a case of SBP in thoracic vertebra with involvement of adjacent disc space. PATIENT...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447985/ https://www.ncbi.nlm.nih.gov/pubmed/34664889 http://dx.doi.org/10.1097/MD.0000000000027288 |
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author | Tan, Hongdong Gu, Jia Xu, Liang Sun, Gang |
author_facet | Tan, Hongdong Gu, Jia Xu, Liang Sun, Gang |
author_sort | Tan, Hongdong |
collection | PubMed |
description | RATIONALE: Solitary bone plasmacytoma (SBP) is a rare manifestation of plasma cell tumor. Although axial skeleton is the most frequently affected site of SBP, adjacent disc space involvement is rare. Herein we report a case of SBP in thoracic vertebra with involvement of adjacent disc space. PATIENT CONCERNS: A 57-year-old male presented with a 2-year history of intermittent back pain with activity. The patient's back pain intensity with activity was a score of 5 of the 10-point visual analog scale). DIAGNOSES AND INTERVENTION: The patient underwent a posterior fusion procedure from T6 to T10, and an open biopsy of the vertebral lesion confirmed that final diagnosis of SBP. The patient received postoperative radiotherapy with a total of 4000 Gy to the T7–T9 vertebral levels over a 20-day period. OUTCOMES: Following radiotherapy, the patient's pain intensity was reduced to the visual analog scale score of 1 at the 6-month follow-up. LESSONS: SBP lacks typical clinical symptoms, and the accurate diagnosis before clinical intervention remains challenging. Due to the disc involvement, SBP often manifests as spinal infection. Hence, differential diagnosis in spinal lesions involving the disc should include SBP. |
format | Online Article Text |
id | pubmed-8447985 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-84479852021-09-20 Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report Tan, Hongdong Gu, Jia Xu, Liang Sun, Gang Medicine (Baltimore) 6800 RATIONALE: Solitary bone plasmacytoma (SBP) is a rare manifestation of plasma cell tumor. Although axial skeleton is the most frequently affected site of SBP, adjacent disc space involvement is rare. Herein we report a case of SBP in thoracic vertebra with involvement of adjacent disc space. PATIENT CONCERNS: A 57-year-old male presented with a 2-year history of intermittent back pain with activity. The patient's back pain intensity with activity was a score of 5 of the 10-point visual analog scale). DIAGNOSES AND INTERVENTION: The patient underwent a posterior fusion procedure from T6 to T10, and an open biopsy of the vertebral lesion confirmed that final diagnosis of SBP. The patient received postoperative radiotherapy with a total of 4000 Gy to the T7–T9 vertebral levels over a 20-day period. OUTCOMES: Following radiotherapy, the patient's pain intensity was reduced to the visual analog scale score of 1 at the 6-month follow-up. LESSONS: SBP lacks typical clinical symptoms, and the accurate diagnosis before clinical intervention remains challenging. Due to the disc involvement, SBP often manifests as spinal infection. Hence, differential diagnosis in spinal lesions involving the disc should include SBP. Lippincott Williams & Wilkins 2021-09-17 /pmc/articles/PMC8447985/ /pubmed/34664889 http://dx.doi.org/10.1097/MD.0000000000027288 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 6800 Tan, Hongdong Gu, Jia Xu, Liang Sun, Gang Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title | Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title_full | Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title_fullStr | Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title_full_unstemmed | Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title_short | Solitary bone plasmacytoma of spine with involvement of adjacent disc space: A case report |
title_sort | solitary bone plasmacytoma of spine with involvement of adjacent disc space: a case report |
topic | 6800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447985/ https://www.ncbi.nlm.nih.gov/pubmed/34664889 http://dx.doi.org/10.1097/MD.0000000000027288 |
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