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Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study

The purpose of this retrospective study was to explore the advantages of computed tomography (CT) nano-contrast agent in tumor diagnosis. A total of 100 patients with malignant tumor who were diagnosed in Shaanxi Province Public Hospital between January 2018 and January 2019 were included in this re...

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Detalles Bibliográficos
Autores principales: Zhou, Yong, Zhu, Yufen, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448064/
https://www.ncbi.nlm.nih.gov/pubmed/34664829
http://dx.doi.org/10.1097/MD.0000000000027044
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author Zhou, Yong
Zhu, Yufen
Li, Jian
author_facet Zhou, Yong
Zhu, Yufen
Li, Jian
author_sort Zhou, Yong
collection PubMed
description The purpose of this retrospective study was to explore the advantages of computed tomography (CT) nano-contrast agent in tumor diagnosis. A total of 100 patients with malignant tumor who were diagnosed in Shaanxi Province Public Hospital between January 2018 and January 2019 were included in this retrospective study. They were randomly divided into observation and control groups with 50 patients in each group. The patients in the observation group used new type of nano-contrast agent for examination, and the patients in the control group used traditional iohexol contrast agent for examination. The detection rate, misdiagnosis rate, and incidence of adverse reactions were observed. In addition, single photon emission computed tomography or CT scan was performed on patients to observe the radioactive concentration. The detection rate was 100% in the observation group and 84% in the control group, and the difference between the 2 groups was statistically significant (χ(2) = 8.763, P = .001). The incidence of adverse reactions was 2% in the observation group and 30% in the control group, and the difference between the 2 groups was significantly different (χ(2) = 12.683, P = .000). The radioactive concentration in the observation group was markedly higher than that in the control group (t = 19.692, P = .001). The use of CT nano-contrast agent in tumor diagnosis had higher detection rate of tumor and radioactive concentration, and it had lower misdiagnosis rate and adverse reaction rate than traditional iohexol contrast agent.
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spelling pubmed-84480642021-09-20 Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study Zhou, Yong Zhu, Yufen Li, Jian Medicine (Baltimore) 5700 The purpose of this retrospective study was to explore the advantages of computed tomography (CT) nano-contrast agent in tumor diagnosis. A total of 100 patients with malignant tumor who were diagnosed in Shaanxi Province Public Hospital between January 2018 and January 2019 were included in this retrospective study. They were randomly divided into observation and control groups with 50 patients in each group. The patients in the observation group used new type of nano-contrast agent for examination, and the patients in the control group used traditional iohexol contrast agent for examination. The detection rate, misdiagnosis rate, and incidence of adverse reactions were observed. In addition, single photon emission computed tomography or CT scan was performed on patients to observe the radioactive concentration. The detection rate was 100% in the observation group and 84% in the control group, and the difference between the 2 groups was statistically significant (χ(2) = 8.763, P = .001). The incidence of adverse reactions was 2% in the observation group and 30% in the control group, and the difference between the 2 groups was significantly different (χ(2) = 12.683, P = .000). The radioactive concentration in the observation group was markedly higher than that in the control group (t = 19.692, P = .001). The use of CT nano-contrast agent in tumor diagnosis had higher detection rate of tumor and radioactive concentration, and it had lower misdiagnosis rate and adverse reaction rate than traditional iohexol contrast agent. Lippincott Williams & Wilkins 2021-09-17 /pmc/articles/PMC8448064/ /pubmed/34664829 http://dx.doi.org/10.1097/MD.0000000000027044 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 5700
Zhou, Yong
Zhu, Yufen
Li, Jian
Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title_full Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title_fullStr Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title_full_unstemmed Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title_short Advantages of CT nano-contrast agent in tumor diagnosis: A retrospective study
title_sort advantages of ct nano-contrast agent in tumor diagnosis: a retrospective study
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448064/
https://www.ncbi.nlm.nih.gov/pubmed/34664829
http://dx.doi.org/10.1097/MD.0000000000027044
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