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Lesion Penetration and Activity Limit the Utility of Second-Line Injectable Agents in Pulmonary Tuberculosis

Amikacin and kanamycin are second-line injectables used in the treatment of multidrug-resistant tuberculosis (MDR-TB) based on the clinical utility of streptomycin, another aminoglycoside and first-line anti-TB drug. While streptomycin was tested as a single agent in the first controlled TB clinical...

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Detalles Bibliográficos
Autores principales:	Ernest, Jacqueline P., Sarathy, Jansy, Wang, Ning, Kaya, Firat, Zimmerman, Matthew D., Strydom, Natasha, Wang, Han, Xie, Min, Gengenbacher, Martin, Via, Laura E., Barry, Clifton E., Carter, Claire L., Savic, Radojka M., Dartois, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448094/ https://www.ncbi.nlm.nih.gov/pubmed/34252307 http://dx.doi.org/10.1128/AAC.00506-21

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