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Epetraborole Is Active against Mycobacterium abscessus

Benzoxaboroles are a new class of leucyl-tRNA synthetase inhibitors. We recently reported that the antitubercular 4-halogenated benzoxaboroles are active against Mycobacterium abscessus. Here, we find that the nonhalogenated benzoxaborole epetraborole, a clinical candidate developed for Gram-negativ...

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Detalles Bibliográficos
Autores principales: Ganapathy, Uday S., Gengenbacher, Martin, Dick, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448144/
https://www.ncbi.nlm.nih.gov/pubmed/34280020
http://dx.doi.org/10.1128/AAC.01156-21