Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206

Carbapenem-resistant Acinetobacter baumannii and Enterobacterales are identified as urgent threats, and multidrug-resistant (MDR) Pseudomonas aeruginosa and extended-spectrum beta-lactamase (ESBL)-producing pathogens are identified as serious threats by the Centers for Disease Control and Prevention...

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Detalles Bibliográficos
Autores principales: Bruss, Jon, Lister, Troy, Gupta, Vipul K., Stone, Emily, Morelli, Lisa, Lei, Yang, Melnick, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448162/
https://www.ncbi.nlm.nih.gov/pubmed/34339267
http://dx.doi.org/10.1128/AAC.00739-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448162/
https://www.ncbi.nlm.nih.gov/pubmed/34339267
http://dx.doi.org/10.1128/AAC.00739-21

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