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Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206

Carbapenem-resistant Acinetobacter baumannii and Enterobacterales are identified as urgent threats, and multidrug-resistant (MDR) Pseudomonas aeruginosa and extended-spectrum beta-lactamase (ESBL)-producing pathogens are identified as serious threats by the Centers for Disease Control and Prevention...

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Detalles Bibliográficos
Autores principales:	Bruss, Jon, Lister, Troy, Gupta, Vipul K., Stone, Emily, Morelli, Lisa, Lei, Yang, Melnick, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Experimental Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448162/ https://www.ncbi.nlm.nih.gov/pubmed/34339267 http://dx.doi.org/10.1128/AAC.00739-21

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