Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series

Langerhans cell histiocytosis (LCH) is a common cause of multifocal lytic skeletal lesions in children. However, multifocal osseous tuberculosis can affect children and mimics LCH on imaging, especially in endemic regions. We report cases with atypical manifestations of multifocal osseous tuberculos...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Rashmi, Naranje, Priyanka, Kandasamy, Devasenathipathy, Jana, Manisha, Gupta, Aditya K., Ramateke, Prashant P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Private Ltd. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448238/
https://www.ncbi.nlm.nih.gov/pubmed/34556922
http://dx.doi.org/10.1055/s-0041-1734347
_version_ 1784569193942745088
author Singh, Rashmi
Naranje, Priyanka
Kandasamy, Devasenathipathy
Jana, Manisha
Gupta, Aditya K.
Ramateke, Prashant P.
author_facet Singh, Rashmi
Naranje, Priyanka
Kandasamy, Devasenathipathy
Jana, Manisha
Gupta, Aditya K.
Ramateke, Prashant P.
author_sort Singh, Rashmi
collection PubMed
description Langerhans cell histiocytosis (LCH) is a common cause of multifocal lytic skeletal lesions in children. However, multifocal osseous tuberculosis can affect children and mimics LCH on imaging, especially in endemic regions. We report cases with atypical manifestations of multifocal osseous tuberculosis which were presumptively diagnosed as LCH. The findings of our series of cases suggest that on computed tomography (CT) irregular sclerotic margins, abscess formation, sclerosis of involved bone, and button sequestrum point toward a diagnosis of multifocal osseous tuberculosis, especially in endemic regions.
format Online
Article
Text
id pubmed-8448238
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Thieme Medical and Scientific Publishers Private Ltd.
record_format MEDLINE/PubMed
spelling pubmed-84482382021-09-22 Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series Singh, Rashmi Naranje, Priyanka Kandasamy, Devasenathipathy Jana, Manisha Gupta, Aditya K. Ramateke, Prashant P. Indian J Radiol Imaging Langerhans cell histiocytosis (LCH) is a common cause of multifocal lytic skeletal lesions in children. However, multifocal osseous tuberculosis can affect children and mimics LCH on imaging, especially in endemic regions. We report cases with atypical manifestations of multifocal osseous tuberculosis which were presumptively diagnosed as LCH. The findings of our series of cases suggest that on computed tomography (CT) irregular sclerotic margins, abscess formation, sclerosis of involved bone, and button sequestrum point toward a diagnosis of multifocal osseous tuberculosis, especially in endemic regions. Thieme Medical and Scientific Publishers Private Ltd. 2021-04 2021-07-27 /pmc/articles/PMC8448238/ /pubmed/34556922 http://dx.doi.org/10.1055/s-0041-1734347 Text en Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Singh, Rashmi
Naranje, Priyanka
Kandasamy, Devasenathipathy
Jana, Manisha
Gupta, Aditya K.
Ramateke, Prashant P.
Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title_full Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title_fullStr Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title_full_unstemmed Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title_short Multifocal Osseous Tuberculosis Mimicking Langerhans’ Cell Histiocytosis: A Case Series
title_sort multifocal osseous tuberculosis mimicking langerhans’ cell histiocytosis: a case series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448238/
https://www.ncbi.nlm.nih.gov/pubmed/34556922
http://dx.doi.org/10.1055/s-0041-1734347
work_keys_str_mv AT singhrashmi multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries
AT naranjepriyanka multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries
AT kandasamydevasenathipathy multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries
AT janamanisha multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries
AT guptaadityak multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries
AT ramatekeprashantp multifocalosseoustuberculosismimickinglangerhanscellhistiocytosisacaseseries

Ejemplares similares