Transcriptomic entropy benchmarks stem cell-derived cardiomyocyte maturation against endogenous tissue at single cell level

The immaturity of pluripotent stem cell (PSC)-derived tissues has emerged as a universal problem for their biomedical applications. While efforts have been made to generate adult-like cells from PSCs, direct benchmarking of PSC-derived tissues against in vivo development has not been established. Th...

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Detalles Bibliográficos
Autores principales: Kannan, Suraj, Farid, Michael, Lin, Brian L., Miyamoto, Matthew, Kwon, Chulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448341/
https://www.ncbi.nlm.nih.gov/pubmed/34534204
http://dx.doi.org/10.1371/journal.pcbi.1009305

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