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RhoA- and Cdc42-induced antagonistic forces underlie symmetry breaking and spindle rotation in mouse oocytes

Mammalian oocyte meiotic divisions are highly asymmetric and produce a large haploid gamete and 2 small polar bodies. This relies on the ability of the cell to break symmetry and position its spindle close to the cortex before anaphase occurs. In metaphase II–arrested mouse oocytes, the spindle is a...

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Detalles Bibliográficos
Autores principales: Dehapiot, Benoit, Clément, Raphaël, Bourdais, Anne, Carrière, Virginie, Huet, Sébastien, Halet, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448345/
https://www.ncbi.nlm.nih.gov/pubmed/34491981
http://dx.doi.org/10.1371/journal.pbio.3001376