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Millimeter-scale chip–based supercontinuum generation for optical coherence tomography

Supercontinuum sources for optical coherence tomography (OCT) have raised great interest as they provide broad bandwidth to enable high resolution and high power to improve imaging sensitivity. Commercial fiber-based supercontinuum systems require high pump powers to generate broad bandwidth and cus...

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Detalles Bibliográficos
Autores principales: Ji, Xingchen, Mojahed, Diana, Okawachi, Yoshitomo, Gaeta, Alexander L., Hendon, Christine P., Lipson, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448444/
https://www.ncbi.nlm.nih.gov/pubmed/34533990
http://dx.doi.org/10.1126/sciadv.abg8869
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author Ji, Xingchen
Mojahed, Diana
Okawachi, Yoshitomo
Gaeta, Alexander L.
Hendon, Christine P.
Lipson, Michal
author_facet Ji, Xingchen
Mojahed, Diana
Okawachi, Yoshitomo
Gaeta, Alexander L.
Hendon, Christine P.
Lipson, Michal
author_sort Ji, Xingchen
collection PubMed
description Supercontinuum sources for optical coherence tomography (OCT) have raised great interest as they provide broad bandwidth to enable high resolution and high power to improve imaging sensitivity. Commercial fiber-based supercontinuum systems require high pump powers to generate broad bandwidth and customized optical filters to shape/attenuate the spectra. They also have limited sensitivity and depth performance. We introduce a supercontinuum platform based on a 1-mm(2) Si(3)N(4) photonic chip for OCT. We directly pump and efficiently generate supercontinuum near 1300 nm without any postfiltering. With a 25-pJ pump pulse, we generate a broadband spectrum with a flat 3-dB bandwidth of 105 nm. Integrating the chip into a spectral domain OCT system, we achieve 105-dB sensitivity and 1.81-mm 6-dB sensitivity roll-off with 300-μW optical power on sample. We image breast tissue to demonstrate strong imaging performance. Our chip will pave the way toward portable OCT and incorporating integrated photonics into optical imaging technologies.
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spelling pubmed-84484442021-09-27 Millimeter-scale chip–based supercontinuum generation for optical coherence tomography Ji, Xingchen Mojahed, Diana Okawachi, Yoshitomo Gaeta, Alexander L. Hendon, Christine P. Lipson, Michal Sci Adv Physical and Materials Sciences Supercontinuum sources for optical coherence tomography (OCT) have raised great interest as they provide broad bandwidth to enable high resolution and high power to improve imaging sensitivity. Commercial fiber-based supercontinuum systems require high pump powers to generate broad bandwidth and customized optical filters to shape/attenuate the spectra. They also have limited sensitivity and depth performance. We introduce a supercontinuum platform based on a 1-mm(2) Si(3)N(4) photonic chip for OCT. We directly pump and efficiently generate supercontinuum near 1300 nm without any postfiltering. With a 25-pJ pump pulse, we generate a broadband spectrum with a flat 3-dB bandwidth of 105 nm. Integrating the chip into a spectral domain OCT system, we achieve 105-dB sensitivity and 1.81-mm 6-dB sensitivity roll-off with 300-μW optical power on sample. We image breast tissue to demonstrate strong imaging performance. Our chip will pave the way toward portable OCT and incorporating integrated photonics into optical imaging technologies. American Association for the Advancement of Science 2021-09-17 /pmc/articles/PMC8448444/ /pubmed/34533990 http://dx.doi.org/10.1126/sciadv.abg8869 Text en Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Physical and Materials Sciences
Ji, Xingchen
Mojahed, Diana
Okawachi, Yoshitomo
Gaeta, Alexander L.
Hendon, Christine P.
Lipson, Michal
Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title_full Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title_fullStr Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title_full_unstemmed Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title_short Millimeter-scale chip–based supercontinuum generation for optical coherence tomography
title_sort millimeter-scale chip–based supercontinuum generation for optical coherence tomography
topic Physical and Materials Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448444/
https://www.ncbi.nlm.nih.gov/pubmed/34533990
http://dx.doi.org/10.1126/sciadv.abg8869
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