Cell patterning by secretion-induced plasma membrane flows

Cells self-organize using reaction-diffusion and fluid-flow principles. Whether bulk membrane flows contribute to cell patterning has not been established. Here, using mathematical modeling, optogenetics, and synthetic probes, we show that polarized exocytosis causes lateral membrane flows away from...

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Detalles Bibliográficos
Autores principales: Gerganova, Veneta, Lamas, Iker, Rutkowski, David M., Vještica, Aleksandar, Castro, Daniela Gallo, Vincenzetti, Vincent, Vavylonis, Dimitrios, Martin, Sophie G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448446/
https://www.ncbi.nlm.nih.gov/pubmed/34533984
http://dx.doi.org/10.1126/sciadv.abg6718

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