Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications

There is growing evidence that prenatal immune activation contributes to neuropsychiatric disorders. Here, we show that early postnatal immune activation resulted in profound impairments in social behavior, including in social memory in adult male mice heterozygous for a gene responsible for tuberou...

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Detalles Bibliográficos
Autores principales: López-Aranda, Manuel F., Chattopadhyay, Ishanu, Boxx, Gayle M., Fraley, Elizabeth R., Silva, Tawnie K., Zhou, Miou, Phan, Miranda, Herrera, Isaiah, Taloma, Sunrae, Mandanas, Rochelle, Bach, Karen, Gandal, Michael, Geschwind, Daniel H., Cheng, Genhong, Rzhetsky, Andrey, White, Stephanie A., Silva, Alcino J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448451/
https://www.ncbi.nlm.nih.gov/pubmed/34533985
http://dx.doi.org/10.1126/sciadv.abf2073

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