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Iminodibenzyl induced redirected COX-2 activity inhibits breast cancer progression
Knocking down delta-5-desaturase (D5D) by siRNA or shRNA is a promising strategy to achieve 8-hydroxyoctanoic acid (8-HOA) production for cancer inhibition. However, the RNAi-based strategy to stimulate 8-HOA is restricted due to endonucleases mediated physiological degradation and off-target effect...
Autores principales: | Shah, Harshit, Pang, Lizhi, Qian, Steven, Sathish, Venkatachalem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448825/ https://www.ncbi.nlm.nih.gov/pubmed/34535685 http://dx.doi.org/10.1038/s41523-021-00330-9 |
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