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Argininosuccinate lyase is a metabolic vulnerability in breast development and cancer

Epithelial-to-mesenchymal transition (EMT) is fundamental to both normal tissue development and cancer progression. We hypothesized that EMT plasticity defines a range of metabolic phenotypes and that individual breast epithelial metabolic phenotypes are likely to fall within this phenotypic landsca...

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Detalles Bibliográficos
Autores principales: Karvelsson, Sigurdur Trausti, Wang, Qiong, Hilmarsdottir, Bylgja, Sigurdsson, Arnar, Moestue, Siver Andreas, Mælandsmo, Gunhild Mari, Halldorsson, Skarphedinn, Gudmundsson, Steinn, Rolfsson, Ottar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448827/
https://www.ncbi.nlm.nih.gov/pubmed/34535676
http://dx.doi.org/10.1038/s41540-021-00195-5

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