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IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment
Ependymal cells have multiple apical cilia that line the ventricular surfaces and the central canal of spinal cord. In cancer, the loss of ependymal cell polarity promotes the formation of different types of tumors, such as supratentorial anaplastic ependymomas, which are highly aggressive in childr...
Autores principales: | Baeza, Victor, Cifuentes, Manuel, Martínez, Fernando, Ramírez, Eder, Nualart, Francisco, Ferrada, Luciano, Oviedo, María José, De Lima, Isabelle, Troncoso, Ninoschka, Saldivia, Natalia, Salazar, Katterine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448829/ https://www.ncbi.nlm.nih.gov/pubmed/34535732 http://dx.doi.org/10.1038/s41598-021-97948-3 |
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