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A glutamine sensor that directly activates TORC1

TOR complex 1 (TORC1) is an evolutionarily-conserved protein kinase that controls cell growth and metabolism in response to nutrients, particularly amino acids. In mammals, several amino acid sensors have been identified that converge on the multi-layered machinery regulating Rag GTPases to trigger...

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Detalles Bibliográficos
Autores principales: Tanigawa, Mirai, Yamamoto, Katsuyoshi, Nagatoishi, Satoru, Nagata, Koji, Noshiro, Daisuke, Noda, Nobuo N., Tsumoto, Kouhei, Maeda, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448839/
https://www.ncbi.nlm.nih.gov/pubmed/34535752
http://dx.doi.org/10.1038/s42003-021-02625-w

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