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ADAR-mediated RNA editing of DNA:RNA hybrids is required for DNA double strand break repair

The maintenance of genomic stability requires the coordination of multiple cellular tasks upon the appearance of DNA lesions. RNA editing, the post-transcriptional sequence alteration of RNA, has a profound effect on cell homeostasis, but its implication in the response to DNA damage was not previou...

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Detalles Bibliográficos
Autores principales:	Jimeno, Sonia, Prados-Carvajal, Rosario, Fernández-Ávila, María Jesús, Silva, Sonia, Silvestris, Domenico Alessandro, Endara-Coll, Martín, Rodríguez-Real, Guillermo, Domingo-Prim, Judit, Mejías-Navarro, Fernando, Romero-Franco, Amador, Jimeno-González, Silvia, Barroso, Sonia, Cesarini, Valeriana, Aguilera, Andrés, Gallo, Angela, Visa, Neus, Huertas, Pablo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448848/ https://www.ncbi.nlm.nih.gov/pubmed/34535666 http://dx.doi.org/10.1038/s41467-021-25790-2

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