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Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target

Novel coronavirus disease 2019 (COVID-19) has emerged as a global pandemic with far-reaching societal impact. Here we demonstrate that Pin1 is a key cellular molecule necessary for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) propagation. In this study, siRNA-mediated silencing of Pi...

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Detalles Bibliográficos
Autores principales:	Yamamotoya, Takeshi, Nakatsu, Yusuke, Kanna, Machi, Hasei, Shun, Ohata, Yukino, Encinas, Jeffrey, Ito, Hisanaka, Okabe, Takayoshi, Asano, Tomoichiro, Sakaguchi, Takemasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448864/ https://www.ncbi.nlm.nih.gov/pubmed/34535740 http://dx.doi.org/10.1038/s41598-021-97972-3

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