Prodromal dysfunction of α5GABA-A receptor modulated hippocampal ripples occurs prior to neurodegeneration in the TgF344-AD rat model of Alzheimer's disease

Decades of research attempting to slow the onset of Alzheimer's disease (AD) indicates that a better understanding of memory will be key to the discovery of effective therapeutic approaches. Here, we ask whether prodromal neural network dysfunction might occur in the hippocampal trisynaptic cir...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratner, Marcia H., Downing, Scott S., Guo, Ouyang, Odamah, KathrynAnn E., Stewart, Tara M., Kumaresan, Vidhya, Robitsek, R. Jonathan, Xia, Weiming, Farb, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449175/
https://www.ncbi.nlm.nih.gov/pubmed/34568591
http://dx.doi.org/10.1016/j.heliyon.2021.e07895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449175/
https://www.ncbi.nlm.nih.gov/pubmed/34568591
http://dx.doi.org/10.1016/j.heliyon.2021.e07895

Ejemplares similares