Prodromal dysfunction of α5GABA-A receptor modulated hippocampal ripples occurs prior to neurodegeneration in the TgF344-AD rat model of Alzheimer's disease

Decades of research attempting to slow the onset of Alzheimer's disease (AD) indicates that a better understanding of memory will be key to the discovery of effective therapeutic approaches. Here, we ask whether prodromal neural network dysfunction might occur in the hippocampal trisynaptic cir...

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Detalles Bibliográficos
Autores principales: Ratner, Marcia H., Downing, Scott S., Guo, Ouyang, Odamah, KathrynAnn E., Stewart, Tara M., Kumaresan, Vidhya, Robitsek, R. Jonathan, Xia, Weiming, Farb, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449175/
https://www.ncbi.nlm.nih.gov/pubmed/34568591
http://dx.doi.org/10.1016/j.heliyon.2021.e07895

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