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Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice

Cellular cholesterol is regulated by at least two transcriptional mechanisms involving sterol-regulatory-element-binding proteins (SREBPs) and liver X receptors (LXRs). Although SREBP and LXR pathways are the predominant mechanisms that sense cholesterol in the endoplasmic reticulum and nucleus to a...

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Detalles Bibliográficos
Autores principales:	Dalton, George D., Oh, Seh-Hoon, Tang, Linda, Zhang, Stephanie, Brown, Amanda L., Varadharajan, Venkateshwari, Baleanu-Gogonea, Camelia, Gogonea, Valentin, Pathak, Preeti, Brown, J. Mark, Diehl, Anna Mae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449244/ https://www.ncbi.nlm.nih.gov/pubmed/34568800 http://dx.doi.org/10.1016/j.isci.2021.103089

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