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Activity of the yeast vacuolar TRP channel TRPY1 is inhibited by Ca(2+)–calmodulin binding

Transient receptor potential (TRP) cation channels, which are conserved across mammals, flies, fish, sea squirts, worms, and fungi, essentially contribute to cellular Ca(2+) signaling. The activity of the unique TRP channel in yeast, TRP yeast channel 1 (TRPY1), relies on the vacuolar and cytoplasmi...

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Detalles Bibliográficos
Autores principales: Amini, Mahnaz, Chang, Yiming, Wissenbach, Ulrich, Flockerzi, Veit, Schlenstedt, Gabriel, Beck, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449268/
https://www.ncbi.nlm.nih.gov/pubmed/34461097
http://dx.doi.org/10.1016/j.jbc.2021.101126