Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity

A disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) is a multidomain metalloprotease for which until now only a single substrate has been identified. ADAMTS13 cleaves the polymeric force-sensor von Willebrand factor (VWF) that unfolds under shear stress and r...

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Detalles Bibliográficos
Autores principales: Ercig, Bogac, Arfman, Tom, Hrdinova, Johana, Wichapong, Kanin, Reutelingsperger, Chris P.M., Vanhoorelbeke, Karen, Nicolaes, Gerry A.F., Voorberg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449270/
https://www.ncbi.nlm.nih.gov/pubmed/34461090
http://dx.doi.org/10.1016/j.jbc.2021.101132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449270/
https://www.ncbi.nlm.nih.gov/pubmed/34461090
http://dx.doi.org/10.1016/j.jbc.2021.101132

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