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Structural features of Cryptococcus neoformans bifunctional GAR/AIR synthetase may present novel antifungal drug targets

Cryptococcus neoformans is a fungus that causes life-threatening systemic mycoses. During infection of the human host, this pathogen experiences a major change in the availability of purines; the fungus can scavenge the abundant purines in its environmental niche of pigeon excrement, but must employ...

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Detalles Bibliográficos
Autores principales:	Chua, Sheena M.H., Wizrah, Maha S.I., Luo, Zhenyao, Lim, Bryan Y.J., Kappler, Ulrike, Kobe, Bostjan, Fraser, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449271/ https://www.ncbi.nlm.nih.gov/pubmed/34416230 http://dx.doi.org/10.1016/j.jbc.2021.101091

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