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A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion

Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong immunosuppression regimens. This challenge has prompted the development of macroencapsulation devices (MEDs) to immunoprotect the transplanted islets. While promising, conventional MEDs are faced with insuf...

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Detalles Bibliográficos
Autores principales: Yang, Kisuk, O’Cearbhaill, Eoin D., Liu, Sophie S., Zhou, Angela, Chitnis, Girish D., Hamilos, Allison E., Xu, Jun, Verma, Mohan K. S., Giraldo, Jaime A., Kudo, Yoshimasa, Lee, Eunjee A., Lee, Yuhan, Pop, Ramona, Langer, Robert, Melton, Douglas A., Greiner, Dale L., Karp, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449352/
https://www.ncbi.nlm.nih.gov/pubmed/34504013
http://dx.doi.org/10.1073/pnas.2101258118