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A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion
Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong immunosuppression regimens. This challenge has prompted the development of macroencapsulation devices (MEDs) to immunoprotect the transplanted islets. While promising, conventional MEDs are faced with insuf...
Autores principales: | Yang, Kisuk, O’Cearbhaill, Eoin D., Liu, Sophie S., Zhou, Angela, Chitnis, Girish D., Hamilos, Allison E., Xu, Jun, Verma, Mohan K. S., Giraldo, Jaime A., Kudo, Yoshimasa, Lee, Eunjee A., Lee, Yuhan, Pop, Ramona, Langer, Robert, Melton, Douglas A., Greiner, Dale L., Karp, Jeffrey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449352/ https://www.ncbi.nlm.nih.gov/pubmed/34504013 http://dx.doi.org/10.1073/pnas.2101258118 |
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