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Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018

INTRODUCTION: hematopoietic stem cell transplantation (HSCT) is part of the cellular immunotherapy arsenal. It is used in the treatment of several malignant and non-malignant hematological conditions as well as other extra-hematological diseases. HSCT has been described since 1950 and introduced in...

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Autores principales: Loukhnati, Mehdi, Lahlimi, Fatima Ezzahra, Tazi, Illias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449579/
https://www.ncbi.nlm.nih.gov/pubmed/34584602
http://dx.doi.org/10.11604/pamj.2021.39.176.29029
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author Loukhnati, Mehdi
Lahlimi, Fatima Ezzahra
Tazi, Illias
author_facet Loukhnati, Mehdi
Lahlimi, Fatima Ezzahra
Tazi, Illias
author_sort Loukhnati, Mehdi
collection PubMed
description INTRODUCTION: hematopoietic stem cell transplantation (HSCT) is part of the cellular immunotherapy arsenal. It is used in the treatment of several malignant and non-malignant hematological conditions as well as other extra-hematological diseases. HSCT has been described since 1950 and introduced in Morocco since the 2000s. GSCH is still little used in our context due to several legal, financial and organizational barriers. The purpose of this study is to report the experience of the Bone Marrow Transplant Department of the Marrakech’s Mohammed VI University Hospital with hematopoietic stem cell transplantation, is one of the Hospital Departments in developing countries. METHODS: we carried out a descriptive retrospective study over a period of 6 years. RESULTS: during the study period, sixty-six HSCT were performed. Multiple myeloma was the main indication for HSCT in our case series (30 patients with autografts). In our case series, mortality rate was around 20%, relapse rate was 23% while complications rate was 38%. Despite the challenges, our results were encouraging during the long follow-up period. CONCLUSION: efforts still need to be made to improve therapy results.
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spelling pubmed-84495792021-09-27 Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018 Loukhnati, Mehdi Lahlimi, Fatima Ezzahra Tazi, Illias Pan Afr Med J Research INTRODUCTION: hematopoietic stem cell transplantation (HSCT) is part of the cellular immunotherapy arsenal. It is used in the treatment of several malignant and non-malignant hematological conditions as well as other extra-hematological diseases. HSCT has been described since 1950 and introduced in Morocco since the 2000s. GSCH is still little used in our context due to several legal, financial and organizational barriers. The purpose of this study is to report the experience of the Bone Marrow Transplant Department of the Marrakech’s Mohammed VI University Hospital with hematopoietic stem cell transplantation, is one of the Hospital Departments in developing countries. METHODS: we carried out a descriptive retrospective study over a period of 6 years. RESULTS: during the study period, sixty-six HSCT were performed. Multiple myeloma was the main indication for HSCT in our case series (30 patients with autografts). In our case series, mortality rate was around 20%, relapse rate was 23% while complications rate was 38%. Despite the challenges, our results were encouraging during the long follow-up period. CONCLUSION: efforts still need to be made to improve therapy results. The African Field Epidemiology Network 2021-07-06 /pmc/articles/PMC8449579/ /pubmed/34584602 http://dx.doi.org/10.11604/pamj.2021.39.176.29029 Text en Copyright: Mehdi Loukhnati et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Loukhnati, Mehdi
Lahlimi, Fatima Ezzahra
Tazi, Illias
Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title_full Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title_fullStr Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title_full_unstemmed Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title_short Bilan d’activité de l’unité de greffe de moelle osseuse du Centre Hospitalier Universitaire Mohamed VI de Marrakech, Maroc: 2012-2018
title_sort bilan d’activité de l’unité de greffe de moelle osseuse du centre hospitalier universitaire mohamed vi de marrakech, maroc: 2012-2018
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449579/
https://www.ncbi.nlm.nih.gov/pubmed/34584602
http://dx.doi.org/10.11604/pamj.2021.39.176.29029
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