Cargando…
A single‐domain small protein Med‐ORF10 regulates the production of antitumour agent medermycin in Streptomyces
Med‐ORF10, a single‐domain protein with unknown function encoded by a gene located in a gene cluster responsible for the biosynthesis of a novel antitumour antibiotic medermycin, shares high homology to a group of small proteins widely distributed in many aromatic polyketide antibiotic pathways. Thi...
Autores principales: | Cai, Xiaofeng, Li, Caiyun, Ichinose, Koji, Jiang, Yali, Liu, Ming, Wang, Huili, Gong, Caixia, Li, Le, Wan, Juan, Zhao, Yiming, Yang, Qing, Li, Aiying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449675/ https://www.ncbi.nlm.nih.gov/pubmed/34139068 http://dx.doi.org/10.1111/1751-7915.13834 |
Ejemplares similares
-
Functional Characterization of a Ketoreductase-Encoding Gene med-ORF12 Involved in the Formation of a Stereospecific Pyran Ring during the Biosynthesis of an Antitumor Antibiotic Medermycin
por: He, Qiang, et al.
Publicado: (2015) -
Accumulation of a Bioactive Benzoisochromanequinone Compound Kalafungin by a Wild Type Antitumor-Medermycin-Producing Streptomycete Strain
por: Lü, Jin, et al.
Publicado: (2015) -
Medermycin Inhibits TNFα-Promoted Inflammatory Reaction in Human Synovial Fibroblasts
por: Inoue, Sho, et al.
Publicado: (2023) -
Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons
por: Yin, Shupeng, et al.
Publicado: (2022) -
Phase I trials of antitumour agents: fundamental concepts
por: Toloi, Diego de Araujo, et al.
Publicado: (2015)