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Gene Expression-Assisted Cancer Prediction Techniques
Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449724/ https://www.ncbi.nlm.nih.gov/pubmed/34545300 http://dx.doi.org/10.1155/2021/4242646 |
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author | Thakur, Tanima Batra, Isha Luthra, Monica Vimal, Shanmuganathan Dhiman, Gaurav Malik, Arun Shabaz, Mohammad |
author_facet | Thakur, Tanima Batra, Isha Luthra, Monica Vimal, Shanmuganathan Dhiman, Gaurav Malik, Arun Shabaz, Mohammad |
author_sort | Thakur, Tanima |
collection | PubMed |
description | Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and then RNA to protein. This protein serves so many purposes, such as creating cells, drugs for cancer, and even hybrid species. As genes carry genetic information from one generation to another, some gene deformity is also transferred to the next generation. Therefore, the deformity needs to be detected. There are many techniques available in the literature to predict cancerous and noncancerous genes from gene expression data. This is an important development from the point of diagnostics and giving a prognosis for the condition. This paper will present a review of some of those techniques from the literature; details about the various datasets on which these techniques are implemented and the advantages and disadvantages. |
format | Online Article Text |
id | pubmed-8449724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-84497242021-09-19 Gene Expression-Assisted Cancer Prediction Techniques Thakur, Tanima Batra, Isha Luthra, Monica Vimal, Shanmuganathan Dhiman, Gaurav Malik, Arun Shabaz, Mohammad J Healthc Eng Review Article Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and then RNA to protein. This protein serves so many purposes, such as creating cells, drugs for cancer, and even hybrid species. As genes carry genetic information from one generation to another, some gene deformity is also transferred to the next generation. Therefore, the deformity needs to be detected. There are many techniques available in the literature to predict cancerous and noncancerous genes from gene expression data. This is an important development from the point of diagnostics and giving a prognosis for the condition. This paper will present a review of some of those techniques from the literature; details about the various datasets on which these techniques are implemented and the advantages and disadvantages. Hindawi 2021-08-19 /pmc/articles/PMC8449724/ /pubmed/34545300 http://dx.doi.org/10.1155/2021/4242646 Text en Copyright © 2021 Tanima Thakur et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Thakur, Tanima Batra, Isha Luthra, Monica Vimal, Shanmuganathan Dhiman, Gaurav Malik, Arun Shabaz, Mohammad Gene Expression-Assisted Cancer Prediction Techniques |
title | Gene Expression-Assisted Cancer Prediction Techniques |
title_full | Gene Expression-Assisted Cancer Prediction Techniques |
title_fullStr | Gene Expression-Assisted Cancer Prediction Techniques |
title_full_unstemmed | Gene Expression-Assisted Cancer Prediction Techniques |
title_short | Gene Expression-Assisted Cancer Prediction Techniques |
title_sort | gene expression-assisted cancer prediction techniques |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449724/ https://www.ncbi.nlm.nih.gov/pubmed/34545300 http://dx.doi.org/10.1155/2021/4242646 |
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