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Gene Expression-Assisted Cancer Prediction Techniques

Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and...

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Autores principales: Thakur, Tanima, Batra, Isha, Luthra, Monica, Vimal, Shanmuganathan, Dhiman, Gaurav, Malik, Arun, Shabaz, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449724/
https://www.ncbi.nlm.nih.gov/pubmed/34545300
http://dx.doi.org/10.1155/2021/4242646
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author Thakur, Tanima
Batra, Isha
Luthra, Monica
Vimal, Shanmuganathan
Dhiman, Gaurav
Malik, Arun
Shabaz, Mohammad
author_facet Thakur, Tanima
Batra, Isha
Luthra, Monica
Vimal, Shanmuganathan
Dhiman, Gaurav
Malik, Arun
Shabaz, Mohammad
author_sort Thakur, Tanima
collection PubMed
description Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and then RNA to protein. This protein serves so many purposes, such as creating cells, drugs for cancer, and even hybrid species. As genes carry genetic information from one generation to another, some gene deformity is also transferred to the next generation. Therefore, the deformity needs to be detected. There are many techniques available in the literature to predict cancerous and noncancerous genes from gene expression data. This is an important development from the point of diagnostics and giving a prognosis for the condition. This paper will present a review of some of those techniques from the literature; details about the various datasets on which these techniques are implemented and the advantages and disadvantages.
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spelling pubmed-84497242021-09-19 Gene Expression-Assisted Cancer Prediction Techniques Thakur, Tanima Batra, Isha Luthra, Monica Vimal, Shanmuganathan Dhiman, Gaurav Malik, Arun Shabaz, Mohammad J Healthc Eng Review Article Cancer is one of the deadliest diseases and with its growing number, its detection and treatment become essential. Researchers have developed various methods based on gene expression. Gene expression is a process that is used to convert deoxyribose nucleic acid (DNA) to ribose nucleic acid (RNA) and then RNA to protein. This protein serves so many purposes, such as creating cells, drugs for cancer, and even hybrid species. As genes carry genetic information from one generation to another, some gene deformity is also transferred to the next generation. Therefore, the deformity needs to be detected. There are many techniques available in the literature to predict cancerous and noncancerous genes from gene expression data. This is an important development from the point of diagnostics and giving a prognosis for the condition. This paper will present a review of some of those techniques from the literature; details about the various datasets on which these techniques are implemented and the advantages and disadvantages. Hindawi 2021-08-19 /pmc/articles/PMC8449724/ /pubmed/34545300 http://dx.doi.org/10.1155/2021/4242646 Text en Copyright © 2021 Tanima Thakur et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Thakur, Tanima
Batra, Isha
Luthra, Monica
Vimal, Shanmuganathan
Dhiman, Gaurav
Malik, Arun
Shabaz, Mohammad
Gene Expression-Assisted Cancer Prediction Techniques
title Gene Expression-Assisted Cancer Prediction Techniques
title_full Gene Expression-Assisted Cancer Prediction Techniques
title_fullStr Gene Expression-Assisted Cancer Prediction Techniques
title_full_unstemmed Gene Expression-Assisted Cancer Prediction Techniques
title_short Gene Expression-Assisted Cancer Prediction Techniques
title_sort gene expression-assisted cancer prediction techniques
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8449724/
https://www.ncbi.nlm.nih.gov/pubmed/34545300
http://dx.doi.org/10.1155/2021/4242646
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